Breathing, Swallowing and Voice in Laryngeal Disorders

.........................................................................................................................6 List of original publications..................................................................................................8 Abbreviations...................................................................................................................9 Introduction..................................................................................................................10 Review of literature.............................................................................................................13 Physiology of the normal larynx..............................................................................13 Prevalence of laryngeal cancer...............................................................................19 Reconstruction of speech after total laryngectomy................................................19 Impact of ACD on swallowing and the voice...........................................................21 Reconstruction of the voice in unilateral vocal cord paralysis.................................22 Impact of VCD on breathing and the voice............................................................23 Evaluation methods for laryngeal disorders.......................................................24 Videolaryngostroboscopy.........................................................................24 Perceptual voice analysis.......................................................................................25 Acoustic voice analysis...........................................................................................26 Self-perceived handicap measures of the voice......................................................27 Maximum phonation time...................................................................................27 FEV1......................................................................................................................28 Evaluation of swallowing with videofluorography and FEES...............................28 Laryngeal electromyography...............................................................................29 Health Related Quality of Life (HRQoL)...............................................................30 Aims of the study..................................................................................................................31 Patients and methods..........................................................................................................32 Provox FreeHands in speech reconstruction after total laryngectomy (I)..............32 Dysphonia and dysphagia after ACD (II)..............................................................33 Long-term results after ILAF (III)........................................................................34 Diagnosing exercise-induced laryngeal dyspnea (IV)...........................................35 Statistical methods..................................................................................................36 Results...........................................................................................................37 Provox FreeHands in speech reconstruction after total laryngectomy (I)............37 Dysphonia and dysphagia after ACD (II).................................................................38 Long-term results after ILAF (III)..........................................................................40 Diagnosing exercise-induced laryngeal dyspnea (IV)............................................41 Discussion.......................................................................................................43 Conclusions.... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .51 Acknowledgements......................................................................................................52 References........................................................................................................................54 Original publications...........................................................................................................61